Clinical Applications of Quantitative Imaging
Driven by the mission "to improve the lives of those impacted by disease and disability",
VirtualScopics is taking its technology to the clinic.
Having proven the success of quantitative imaging in drug development, VirtualScopics is now adapting its technology to assist physicians in the personalized treatment of their patients. Similar to the drug development environment of the past, imaging in the clinic is predominantly qualitative, leading to subjective assessments on a patient's disease progression and related response to therapy. VirtualScopics is looking to change this paradigm.
Utilizing an adaptation of the quantitative image analysis platform it uses in drug development, VirtualScopics will be able to assist physicians in the earlier assessment of a patient's disease progression and the effectiveness of a chosen therapy. Armed with earlier access to more accurate information, physicians will be empowered to make a much sooner determination of the effectiveness of a particular therapy and whether a change to the treatment plan needs to be made.
Assessments in 48 hours - Oncology
To emphasize how valuable a tool like quantitative imaging can be to a physician consider the case of a cancer patient undergoing anti-angiogenic therapy. With the typical response rate of anti-angiogenic therapies at 30% or less, it is vital to determine as early as possible whether a patient is not responding to a treatment. Unfortunately, current conventional analysis requires 2 months to make that determination. However, using quantitative imaging VirtualScopics can assess response to therapy within 48 hours (compare the change in blood flow in the below images from Baseline to Day 2). This dramatic difference provides oncologists and patients with valuable time to alter plans if no response is seen.
Expansion Across Therapeutic Areas
As we have proven in the area of drug development, the benefits of quantitative imaging can be expressed across numerous therapeutic areas. Likewise, quantitative assessments can be applied in the clinical setting to provide an early indication of a patient's response to therapy and an early diagnostic tool in key therapeutic areas such as cardiovascular, central nervous system and musculoskeletal. Key quantitative assessments include the following:
- Tumor Volume
- Blood Flow Reduction
- Plaque burden/volume
- Coronary artery burden
- Calcification measurements
- Plaque composition (vulnerable vs. stable)
Central Nervous System
- Brain Volume (MS, Alzheimer's)
- Hippocampus Volume (Alzheimer's, epilepsy)
- Ventricle Volume
- Liver Fat Ratio (Diabetes)
- Cartilage Volume (OA, Cartilage Repair)
- Perfusion/Synovial Volume (RA)
With this expansion of our offerings VirtualScopics is helping improve patients' lives today and tomorrow.
We have filed a 510K with the FDA for approval of our first clinical application to be used as a treatment effectiveness tool.